Processing of Pre-MicroRNA to MicroRNA Research Paper

Processing of Pre-MicroRNA to MicroRNA - Research Paper Example Thus, the paper will also discuss the five activities of the processing of pre-MicroRNA into MicroRNA (Grosshans & Slack, 2002, pp.17-19). In the study involving photogenic elements, scientists normally use samples from animals before testing their results on human beings. In most biochemical laborites, one would find mice especially the Drosophila, Arabidopsis, and elegans type. These animals provide some useful biochemical samples, which scientists study to inform on certain biological and biochemical issues. Just like human beings, mice also have microRNA. Through cloning and sequencing, scientists extract microRNA for study purposes. Various studies have shown that both human beings and mice have over two hundred to three hundred inimitable microRNA genes. The studies also explain that in organisms, human beings and mice included, microRNAs are homologous in nature. Consequently, this is a clear indication that microRNAs play significant roles by representing comparatively old and essential regulatory pathways (Gallo et al., 2006, pp.6156-6159). As seen above, the genome hosts pre-MicroRNA and other photogenic elements. Within the genome, sequence encoding of microRNA takes place. However, since there are mechanisms that control microRNA expression, the encoding of microRNA will involve only known genes. In most cases, these genes occur in various flimsy locations within the human chromosomes, and one of the chief characteristic about them their independently transcription shape. It is imperative to note that the primary microRNA transcripts (pre-microRNA) are the ones that encode strands of microRNA. In general, such encoding produces the microRNAs that have the same orientation as pre-microRNA. Clearly, this is an indication that there is a microRNA promoter, which is responsible for such transcriptions. In most cases, the genome stores microRNA genes, and here, these genes appear in form of cluster.